Daporinad (hydrochloride), CAS [[2727965-45-7]] Preis auf Anfrage

Product Overview

• Article Name: Daporinad (hydrochloride), CAS [[2727965-45-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-50876A
• Supplier Catalog Number: HY-50876A
• Alternative Catalog Number: MCE-HY-50876A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: FK866 (hydrochloride), APO866 (hydrochloride)

Product Description

Daporinad (FK866) hydrochloride is a non-competitive inhibitor of nicotinamide phosphoribosyltransferase (Nampt), with a Ki value of 0.3 nM. Daporinad hydrochloride depletes NAD+ and ATP levels, inhibits mTORC1 and MAPK/ERK pathways, and activates TFEB to induce autophagy. Daporinad hydrochloride causes the depletion of the endoplasmic reticulum Ca pool, ultimately weakening the mitogen-induced Ca signal and the activation and function of T cells. Daporinad hydrochloride induces cell cycle arrest and apoptosis, and inhibits cell proliferation. Daporinad hydrochloride can be used for the study of myeloma, liver cancer, and immunosuppression[1][2][3][4].

Product Properties

• Molecular Weight: 427.97
• CAS Number: [2727965-45-7]
• Formula: C24H30ClN3O2
• Target: Apoptosis,Autophagy,ERK,mTOR,NAMPT,p38 MAPK

Application Notes

• Application Notes: MCE Product type: Reference compound