Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM)[1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al[2][3].
Molecular Weight:
302.34
Purity:
99.89
CAS Number:
[133865-89-1]
Formula:
C17H19FN2O2
Target:
Monoamine Oxidase
Application Notes:
MCE Product type: Reference compound
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