MNS, CAS [[1485-00-3]]

Product Overview

• Article Name: MNS, CAS [[1485-00-3]]
• Biozol Catalog Number: MCE-HY-78263
• Supplier Catalog Number: HY-78263
• Alternative Catalog Number: MCE-HY-78263-200MG,MCE-HY-78263-100MG,MCE-HY-78263-500MG,MCE-HY-78263-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: NSC 170724, 5-(2-Nitrovinyl)benzodioxole

Product Description

MNS (NSC 170724), the beta-nitrostyrene derivative, is an orally active tyrosine kinase inhibitor and a broad-spectrum antiplatelet agent. MNS inhibits Src, Syk, and FAK with IC50 of 27.3, 2.8, and 97.6 µM, respectively. MNS inhibits NLRP3 inflammasome and beta1 integrin. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 µM, respectively. MNS is cytotoxic to a variety of cells[1][2][3][4][5][6][7][8][9].

Product Properties

• Molecular Weight: 193.16
• Purity: 99.60
• CAS Number: [1485-00-3]
• Formula: C9H7NO4
• Target: Integrin,NOD-like Receptor (NLR),Src,Syk

Application Notes

• Application Notes: MCE Product type: Reference compound