Glycocholic acid (hydrate), CAS [[1192657-83-2]]

Product Overview

• Article Name: Glycocholic acid (hydrate), CAS [[1192657-83-2]]
• Biozol Catalog Number: MCE-HY-N1423B
• Supplier Catalog Number: HY-N1423B
• Alternative Catalog Number: MCE-HY-N1423B-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Glycocholic acid hydrate is a bile acid derivative. Glycocholic acid hydrate downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid hydrate inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid hydrate modulates related bile acid receptor signaling. Glycocholic acid hydrate suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid hydrate can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA)[1][2][3].

Product Properties

• Purity: 97
• CAS Number: [1192657-83-2]
• Formula: C26H43NO6.xH2O
• Target: Apoptosis,Bacterial,Bcl-2 Family,Caspase,Endogenous Metabolite,FXR,G protein-coupled Bile Acid Receptor 1,LPL Receptor,MDM-2/p53,P-glycoprotein

Application Notes

• Application Notes: MCE Product type: Natural Products