QPH-FR, a quinoa peptide, is a leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) inhibitor. QPH-FR competitively suppresses the formation of the LGR5/RSPO1 complex by binding to LGR5. QPH-FR causes RNF43/ZNRF3 to ubiquitinate the FZD receptor, thereby suppressing the Wnt/beta-catenin signaling pathway and exerting stemness inhibition[1].
Molecular Weight:
1862.01
Purity:
98.96
Formula:
C81H124N26O25
Target:
Wnt,beta-catenin
Application Notes:
Peptides
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