EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species. EK1 shows substantially improved pan-CoV fusion inhibitory activity. EK1 potently inhibits SARS-CoV-2. EK1 can form a stable six-helix bundle (6HB) structure with both short alpha-hCoV and long beta-hCoV N-terminal heptad repeats[1].
Molecular Weight:
4331.93
Formula:
C196H317N43O64S
Target:
SARS-CoV
Application Notes:
Peptides
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