Coagulation Factor III (F3), or Tissue Factor (TF), initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex critically activates factors IX or X through limited proteolysis, initiating the coagulation cascade on the cell surface. F3s interaction with HSPE, inhibited by heparin, promotes the generation of activated factor X, emphasizing its central role in regulating hemostatic processes. Coagulation Factor III/F3 Protein, Canine (HEK293, His) is the recombinant canine-derived Coagulation Factor III/F3 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 35-45 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
490153(Gene_ID)Q4W6L5 (T35-E248)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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