Fresolimumab, CAS [[948564-73-6]]

Product Overview

• Article Name: Fresolimumab, CAS [[948564-73-6]]
• Biozol Catalog Number: MCE-HY-P99020
• Supplier Catalog Number: HY-P99020
• Alternative Catalog Number: MCE-HY-P99020-1MG,MCE-HY-P99020-25MG,MCE-HY-P99020-5MG,MCE-HY-P99020-10MG
• Manufacturer: MedchemExpress
• Category: Antikörper
• Alternative Names: GC1008

Product Description

Fresolimumab (GC1008) is a human monoclonal antibody against TGF-beta that neutralizes all mammalian active subtypes of TGF-beta. The binding affinity of Fresolimumab to TGF-beta2 is 1.8 nM. Fresolimumab improves Bleomycin (HY-108345)-induced acute lung injury. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-beta expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease[1][2][3][4].

Product Properties

• Molecular Weight: (144.4 kDa)
• Purity: 99.51
• CAS Number: [948564-73-6]
• Target: TGF-beta/Smad

Application Notes

• Application Notes: Inhibitory Antibodies