Ianalumab (FUT8-KO) is an anti-BAFF-R monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Ianalumab (FUT8-KO) can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF[1].
Molecular Weight:
(146.44 kDa)
Purity:
99.85
Target:
Apoptosis,TNF Receptor
Application Notes:
MCE Product type: Inhibitory Antibodies
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