Methylhydroquinone is an orally active COX inhibitor with IC50s of 480.7 µM and 52.2 µM for ovine COX-1 and human recombinant COX-2, respectively. Methylhydroquinone has potential DNA damaging effects: 1) inhibiting COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity, 2) inducing DNA single-strand breaks. Methylhydroquinone exerts its effects by competitively binding to the active sites of COX-1 (such as Tyr385, Met522) and non-covalent interactions[1][2].
Molecular Weight:
124.14
Purity:
99.96
CAS Number:
[95-71-6]
Formula:
C7H8O2
Target:
COX
Application Notes:
MCE Product type: Natural Products
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