Inosine-5-diphosphate disodium (IDP disodium) is a decoy substrate of NM23-H2. Inosine-5-diphosphate disodium has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 µM). Inosine-5-diphosphate disodium abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5-diphosphate disodium has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of gamma-irradiation. Inosine-5-diphosphate disodium can be used for cancers like Burkitts lymphoma and cardiovascular diseases research[1][2][3].
Molecular Weight:
428.19
Purity:
99.08
CAS Number:
[54735-61-4]
Formula:
C10H14N4O11P2
Target:
Apoptosis,c-Myc
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
