FMF-04-159-2 is a potent covalent cell cycle protein-dependent kinase 14 (CDK14) inhibitor with IC50 of 39.6 nM for CDK14 and 256 nM for CDK2.FMF-04-159-2 is able to reduce alpha-synuclein (alpha-Syn ) aggregation in neurons and plays a role in Parkinsons disease models, and also inhibits triple-negative breast cancer (TNBC) progression and metastasis by attenuating Wnt/beta-catenin signaling.
Molecular Weight:
683.01
Purity:
96.57%
CAS Number:
[2364489-81-4]
Formula:
C28H30Cl3N7O5S
Target:
Others|||Wnt/beta-catenin|||CDK
T11309
* VAT and and shipping costs not included. Errors and price changes excepted