Antibacterial agent 242, a potent inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), demonstrates an IC50 of 5.46 µM against Toxoplasma gondii. It effectively inhibits the enzymatic activity of TgDXR in vitro as well as the proliferation of T. gondii.
Target:
Antibacterial
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