LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 nM as determined by TR-FRET assay, and an EC50 of 76 nM in HepG2 cells. It exhibits favorable pharmacokinetic properties in SD rats and can improve metabolic dysfunction-associated steatohepatitis induced by high-fat diets and CCl4 in mice.
Molecular Weight:
518.53
CAS Number:
[2920000-23-1]
Formula:
C27H29F3N2O5
Target:
FXR
T203062
* VAT and and shipping costs not included. Errors and price changes excepted
