LDHA-IN-9 (Compound 1g) is an LDH-A inhibitor with an IC50 of 25 nM. It inhibits the proliferation of DLD-1 cells by inducing apoptosis, with a GI50 of 27 µM. In mouse models, LDHA-IN-9 exhibits antitumor activity without significant toxicity at a dose of 25 mg/kg.
Molecular Weight:
384.27
CAS Number:
[862719-04-8]
Formula:
C17H22BrNO4
Target:
Apoptosis|||Dehydrogenase
T203085
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