DDO-2728 is a selective pyrazolopyrimidine ALKBH5 inhibitor with an IC50 of 2.97 µM. It enhances the level of N6-methyladenosine (m6A) modification in acute myeloid leukemia (AML) cells and exhibits antiproliferative activity in these cells. Additionally, it demonstrates antitumor efficacy in MV4-11 xenograft models.
Molecular Weight:
578.452
CAS Number:
[3029515-97-4]
Formula:
C28H17F3N4O7
Target:
Others
T205009
* VAT and and shipping costs not included. Errors and price changes excepted