P7-2302 inhibits PDE7 and PDE4B with IC50 values of 0.18 nM and 77.3 nM, respectively. It also inhibits the efflux of P-gp and BCRP (breast cancer resistance protein) and shows low uptake in rat brains. When labeled with 18F, P7-2302 can be used as a PET tracer.
Molecular Weight:
462.87
Formula:
C23H21ClF2N2O4
Target:
PDE
* VAT and and shipping costs not included. Errors and price changes excepted
