c-Met-IN-23 (Compound 12g) functions as a c-Met inhibitor with an IC50 of 0.052 µM against c-Met. It also inhibits the MDR1 and MRP1/2 pumps in cancerous HepG2 and BxPC3 cells. As such, c-Met-IN-23 serves as an anticancer agent.
Formula:
C16H13N7O
Target:
c-Met/HGFR|||P-gp
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