PROTAC SOS1 degrader-10, CAS [[3043923-74-3]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC SOS1 degrader-10, CAS [[3043923-74-3]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T210119
• Supplier Catalog Number: T210119
• Alternative Catalog Number: TGM-T210119-10MG,TGM-T210119-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PROTACSOS1 degrader-10 (Compound 11o) is a degrader of son of sevenless 1 (SOS1) that functions through CRBN- and protease-dependent mechanisms. It effectively degrades SOS1 in KRAS-mutated cancer cells SW620, A549, and DLD-1, with DC50 values of 2.23, 1.85, and 7.53 nM, respectively. Additionally, PROTACSOS1 degrader-10 inhibits the proliferation of SW620, A549, and DLD-1 cells, with IC50 values of 36.7, 52.2, and 107 nM, and suppresses ERK phosphorylation.

Product Properties

• Molecular Weight: 969.1
• CAS Number: [3043923-74-3]
• Formula: C51H63F3N10O6
• Target: PROTACs|||Ras

Images

T210119