LRK-4189 is an orally active, selective PIP4K2C PROTAC degrader with a DC50 <500 nM in MOLT-4 cells. It induces endogenous apoptosis and activates the interferon signaling pathway, exhibiting antitumor activity against microsatellite stable (MSS) colorectal cancer (CRC) cells.
Molecular Weight:
793.9
CAS Number:
[3063346-83-5]
Formula:
C43H49F2N9O4
Target:
PROTACs
T210497
* VAT and and shipping costs not included. Errors and price changes excepted