FGFR2/3-IN-3, CAS [[3069945-78-1]] Preis auf Anfrage

Product Overview

• Article Name: FGFR2/3-IN-3, CAS [[3069945-78-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T210986
• Supplier Catalog Number: T210986
• Alternative Catalog Number: TGM-T210986-10MG,TGM-T210986-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

FGFR2/3-IN-3 is a dual-target FGFR2/3 inhibitor with IC50 values of 2.7 nM (TEL-FGFR2) and 3.9 nM (TEL-FGFR3), displaying efficacy against both wild-type and mutant FGFR3. It exhibits low CYP3A4 inhibition and minimal hERG toxicity. By inhibiting mutant FGFR3-mediated pathways, FGFR2/3-IN-3 improves chondrocyte proliferation and differentiation imbalances, promoting bone growth. In a dwarfism mouse model, it demonstrates growth-promoting effects, indicating potential for treating bone development disorders such as achondroplasia (ACH).

Product Properties

• Molecular Weight: 569.46
• CAS Number: [3069945-78-1]
• Formula: C28H27Cl2FN6O2
• Target: FGFR|||Cytochromes P450

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T210986