MGB1Y is a non-covalent DNA minor groove binder (MGB) that effectively inhibits cancer cell proliferation and topoisomerase I (topoisomerase I) activity. It downregulates breast cancer-related genes in MCF7 and MDA-MB-231 cells. MGB1Y demonstrates broad-spectrum anticancer activity, including against breast cancer, colon cancer, and leukemia.
Target:
DNA Alkylator/Crosslinker|||Topoisomerase|||DNA/RNA Synthesis
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