NOTA-IMB-RGD is a dual-molecule probe that targets integrin alphavbeta3 (integrinalphavbeta3) and programmed death-ligand 1 (PD-L1). It can block the PD-1/PD-L1 signaling pathway and the tumor vasculature with overexpressed integrin alphavbeta3. This compound holds potential for research in solid tumors co-expressing PD-L1 and alphavbeta3, such as gliomas and breast cancer.
Target:
Integrin|||PD-1/PD-L1
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