p-nitro-Pifithrin-alpha, CAS [[389850-21-9]]

Catalog Number: TGM-T21978
Article Name: p-nitro-Pifithrin-alpha, CAS [[389850-21-9]]
Biozol Catalog Number: TGM-T21978
Supplier Catalog Number: T21978
Alternative Catalog Number: TGM-T21978-1MG,TGM-T21978-5MG,TGM-T21978-10MG,TGM-T21978-25MG
Manufacturer: TargetMol
Category: Biochemikalien
p-nitro-Pifithrin-alpha is a cell-permeable analog of pifithrin-alpha, a potent p53 inhibitor. It suppresses p53-mediated TGF-beta1 expression in HK-2 cells and inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. Moreover, p-nitro-Pifithrin-alpha attenuates steatosis and liver injury in mice subjected to a high-fat diet, mitigating the effects of non-alcoholic fatty liver disease [1] [2] [3] [4].
Molecular Weight: 398.27
CAS Number: [389850-21-9]
Formula: C15H16BrN3O3S
Target: TGF-beta/Smad|||Others|||Caspase|||MDM-2/p53
T21978