FzM1, CAS [[1680196-54-6]]

Product Overview

• Article Name: FzM1, CAS [[1680196-54-6]]
• Biozol Catalog Number: TGM-T24076
• Supplier Catalog Number: T24076
• Alternative Catalog Number: TGM-T24076-1MLX10MM(INDMSO),TGM-T24076-1MG,TGM-T24076-5MG,TGM-T24076-10MG,TGM-T24076-25MG,TGM-T24076-50MG,TGM-T24076-100MG,TGM-T24076-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: FzM 1 , FzM-1

Product Description

FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=-6.2) by binding to an allosteric site on intracellular loop 3 (ICL3) of FZD4. This interaction changes the receptors conformation and inhibits the WNT/beta-catenin signaling pathway.

Product Properties

• Molecular Weight: 360.43
• Purity: 99.89%
• CAS Number: [1680196-54-6]
• Formula: C21H16N2O2S
• Target: Wnt/beta-catenin

Images

T24076