PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 0.03 µM) over m-calpain (Ki = 5.33 0.77 µM). Its IC50 values are 0.26 0.03 µM (Ki for µ-calpain) and 5.33 0.77 µM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].
Molecular Weight:
237.25
Purity:
95%
CAS Number:
[179461-52-0]
Formula:
C11H8FNO2S
Target:
Proteasome|||Cysteine Protease
T2493
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