UR-7247 is a novel orally active angiotensin II subtype I (AT1) antagonist, demonstrating very long pharmacological effects. in vivo studies indicate no significant difference between 10 mg UR-7247 and 100 mg losartan four hours post-administration, while in vitro blockade with 100 mg losartan exceeds that observed with UR-7247, confirming UR-7247s extended plasma half-life potentially due to high-affinity protein binding, highlighting its long-lasting, well-tolerated AT1 receptor antagonism in healthy subjects.
Molecular Weight:
430.5
Purity:
98.88%
CAS Number:
[177847-28-8]
Formula:
C24H26N6O2
Target:
RAAS
T29075
T29075
* VAT and and shipping costs not included. Errors and price changes excepted
