PF-04856264 is a Nav1.7 blocker.Nav1.7 is a chondrocyte modulator and a therapeutic target in osteoarthritis.Inhibition of Nav1.7 modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain and inhibits ERK expression, which has analgesic and anti-inflammatory effects.
Molecular Weight:
437.5
Purity:
97.43%
CAS Number:
[1235397-05-3]
Formula:
C20H15N5O3S2
Target:
Sodium Channel
T33943
T33943
* VAT and and shipping costs not included. Errors and price changes excepted