PF-5274857 hydrochloride is a potent, orally active, selective Smo antagonist (IC50=5.8 nM, Ki=4.6 nM) that is permeable through the blood-brain barrier. It has research potential in various tumors, including brain tumors and brain metastases driven by activated Hh pathways.
Molecular Weight:
473.42
CAS Number:
[1613439-62-5]
Formula:
C20H26Cl2N4O3S
Target:
Others|||Smo
T35563
* VAT and and shipping costs not included. Errors and price changes excepted
