Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.
Molecular Weight:
317.38
Purity:
99.44%
CAS Number:
[803712-67-6]
Formula:
C20H19N3O
Target:
Parasite|||Bcl-2 Family|||Autophagy|||Others
T41278
* VAT and and shipping costs not included. Errors and price changes excepted