PBRM1-BD2-IN-2, a selective and cell-active inhibitor of the polybromo-1 (PBRM1) bromodomain, exhibits binding affinity and inhibitory activity specifically targeting the PBRM1-BD2 domain, with Kd and IC50 values of 9.3 µM and 1.0 µM, respectively. This compound is utilized in cancer research.
Molecular Weight:
311.14
Purity:
>99.99%
CAS Number:
[2819989-57-4]
Formula:
C14H9Cl2FN2O
Target:
Epigenetic Reader Domain
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