DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor of MtDHFR, with an IC50 of 7 µM. The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) holds high unexploited potential as a drug target due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1].
Molecular Weight:
227.26
CAS Number:
[331942-46-2]
Formula:
C14H13NO2
Target:
Others|||Antifolate
T60286
* VAT and and shipping costs not included. Errors and price changes excepted