NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.
Molecular Weight:
311.42
Purity:
99.78%
CAS Number:
[1614262-83-7]
Formula:
C20H25NO2
Target:
Antibacterial|||Antibiotic
T60774
* VAT and and shipping costs not included. Errors and price changes excepted
