LPA5 antagonist 1 is a highly potent and selective antagonist of lysophosphatidic acid receptor 5 (LPA5), with an IC50 value of 32 nM. LPA5 antagonist 1 is a small molecule with high brain permeability that significantly alleviates mechanical allodynia in a CFA-induced inflammatory pain model and can be used to study the mechanisms underlying inflammatory and neuropathic pain. LPA5 antagonist 1 is a click chemistry reagent containing an alkyne functional group, capable of undergoing a copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction with molecules bearing an azide group.
Molecular Weight:
486.58
Purity:
98.63%
CAS Number:
[2839471-45-1]
Formula:
C28H26N2O4S
Target:
LPA Receptor
T63231
* VAT and and shipping costs not included. Errors and price changes excepted