AZD0780, CAS [[2455427-91-3]]

Product Overview

• Article Name: AZD0780, CAS [[2455427-91-3]]
• Biozol Catalog Number: TGM-T64362
• Supplier Catalog Number: T64362
• Alternative Catalog Number: TGM-T64362-1MLX10MM(INDMSO),TGM-T64362-1MG,TGM-T64362-5MG,TGM-T64362-10MG,TGM-T64362-25MG,TGM-T64362-50MG,TGM-T64362-100MG,TGM-T64362-200MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: PCSK9-IN-12 , EX-A6975

Product Description

AZD0780 (EX-A6975, PCSK9-IN-12) is an orally active PCSK9 inhibitor with high affinity for PCSK9 (Kd < 200 nM). It binds to a specific pocket in the C-terminal domain of PCSK9 without affecting the PCSK9-LDLR interaction. AZD0780 blocks the lysosomal trafficking of the PCSK9-LDLR complex and prevents PCSK9-induced LDLR degradation, making it useful for studies related to hypercholesterolemia.

Product Properties

• Molecular Weight: 414.41
• Purity: 99.74%
• CAS Number: [2455427-91-3]
• Formula: C20H20F2N6O2
• Target: Others

Images

T64362