Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells.
Molecular Weight:
348.35
CAS Number:
[801-52-5]
Formula:
C16H20N4O5
Target:
Others|||DNA Alkylator/Crosslinker
T68675
* VAT and and shipping costs not included. Errors and price changes excepted
