YM-202074 is a high affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM-202074 binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. It inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells).
Molecular Weight:
414.56
CAS Number:
[299900-83-7]
Formula:
C22H30N4O2S
Target:
Others|||GluR
T69489
* VAT and and shipping costs not included. Errors and price changes excepted