dBRD4-BD1, CAS [[2839318-19-1]]

Product Overview

• Article Name: dBRD4-BD1, CAS [[2839318-19-1]]
• Biozol Catalog Number: TGM-T69506
• Supplier Catalog Number: T69506
• Alternative Catalog Number: TGM-T69506-25MG,TGM-T69506-50MG,TGM-T69506-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

dBRD4-BD1 is a selective BRD4 bromodomain inhibitor. dBRD4-BD1 can selectively degrade BRD4 (DC50 = 280 nM). Notably, dBRD4-BD1 upregulates BRD2/3, a result not observed with degraders using pan-BET ligands. Designing BRD4 selectivity up front enables analysis of BRD4 biology without wider BET-inhibition and simplifies designing BRD4-selective heterobifunctional molecules, such as degraders with new E3 recruiting ligands or for additional probes beyond degraders.

Product Properties

• Molecular Weight: 967
• CAS Number: [2839318-19-1]
• Formula: C50H53F3N8O9
• Target: Others|||Epigenetic Reader Domain|||PROTACs

Images

T69506