Naldemedine tosylate, CAS [[1345728-04-2]]

Product Overview

• Article Name: Naldemedine tosylate, CAS [[1345728-04-2]]
• Biozol Catalog Number: TGM-T70929
• Supplier Catalog Number: T70929
• Alternative Catalog Number: TGM-T70929-25MG, TGM-T70929-50MG, TGM-T70929-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: S-297995 tosylate

Product Description

Naldemedine tosylate (S-297995) is an orally active µ-opioid receptor antagonist (PAMORA) with high binding affinities (K_i = 0.34, 0.43, 0.94 nM) and potent antagonist activities (IC_50 = 25.57, 7.09, 16.1 nM) towards human recombinant µ-, delta-, and kappa-opioid receptors, respectively. It is utilized in research on opioid-induced constipation (OIC) and is anticipated to interact with the 3CL proenzyme encoded by the SARS-CoV-2 genome.

Product Properties

• Molecular Weight: 742.84
• CAS Number: [1345728-04-2]
• Formula: C39H42N4O9S
• Target: Others|||Opioid Receptor