Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kdelta and casein kinase-1-epsilon (CK1epsilon), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 µM for PI3Kdelta and CK1epsilon respectively, it shows unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL). This compound is utilized in the research of hematological malignancies.
Molecular Weight:
743.75
CAS Number:
[1532533-72-4]
Formula:
C38H32F3N5O6S
Target:
PI3K|||Casein Kinase|||Others
T72465
* VAT and and shipping costs not included. Errors and price changes excepted
