HSP70-IN-3, a potent inhibitor of HSP70 with IC50 values of 1.1 µM in ASZ001 cells and 1.9 µM in C3H10T1/2 cells, exhibits anti-Hedgehog (Hh) signaling and anti-proliferative activities. Furthermore, it reduces the expression of the oncogenic transcription factor GLI1 [1].
Molecular Weight:
883.23
Formula:
C48H78N6O7S
Target:
Others|||Hedgehog/Smoothened|||HSP
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