(S,R,S)-AHPC-Me, CAS [[1948273-02-6]]

Product Overview

• Article Name: (S,R,S)-AHPC-Me, CAS [[1948273-02-6]]
• Biozol Catalog Number: TGM-T7752
• Supplier Catalog Number: T7752
• Alternative Catalog Number: TGM-T7752-25MG,TGM-T7752-50MG,TGM-T7752-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: VHL ligand 2 , E3 ligase Ligand 1A

Product Description

(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is an (S,R,S)-AHPC-based VHL ligand used to recruit the von Hippel-Lindau (VHL) protein. It is utilized in the synthesis of ARV-771, a VHL E3 ligase-based BET PROTAC degrader that effectively degrades BET proteins in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.

Product Properties

• Molecular Weight: 444.59
• Purity: 99.86%
• CAS Number: [1948273-02-6]
• Formula: C23H32N4O3S
• Target: E3 Ligase Ligand-Linker Conjugates|||Ligands for E3 Ligase

Images

T7752