DQP-997-74, CAS [[2377187-09-0]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T82528
Supplier Catalog Number:
T82528
Alternative Catalog Number:
TGM-T82528-5MG,TGM-T82528-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Dihydroquinoline-pyrazoline DQP-997-74 (compound 2i) is a selective N-methyl-d-aspartate receptor (NMDAR) inhibitor that preferentially targets GluN2C/D subunits, with IC50 values of 0.069 µM and 0.035 µM, respectively, and possesses blood-brain barrier permeability. It enhances its inhibitory potency in a time-dependent manner when combined with the agonist glutamate, reducing epileptogenic events in a murine model of tuberous sclerosis complex (TSC)-induced epilepsy. DQP-997-74 is potentially applicable for the study of NMDAR-related neurological diseases [1].
Molecular Weight:
570.37
CAS Number:
[2377187-09-0]
Formula:
C28H19Cl2F2N3O4
Target:
Others|||iGluR
T82528
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