IBL-302 (AMU302), an orally available dual-signaling inhibitor targeting PIM and PI3K/AKT/mTOR, is effective against breast cancer and neuroblastoma. It has shown in vivo efficacy in a nude mouse xenograft model by combating trastuzumab resistance. Additionally, IBL-302 augments the effectiveness of widely used cytotoxic chemotherapy drugs such as cisplatin, doxorubicin, and etoposide [1] [2] [3].
Molecular Weight:
567.64
CAS Number:
[1414455-21-2]
Formula:
C25H18FN5O4S3
Target:
Pim|||PI3K|||mTOR|||Akt
T86698
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