IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 µM (FGFR1), 0.25 µM (IGF1R), 0.34 µM (TrkA), and 0.39 µM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimers disease.
Molecular Weight:
387.39
CAS Number:
[2375424-89-6]
Formula:
C22H17N3O4
Target:
EGFR|||Trk receptor|||IGF-1R
T88615
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