Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 µM, respectively. It shows antagonistic activity on rP2X3 (IC50=0.87 µM). It is development as an injectable agent for the treatment of postoperative pain.
Molecular Weight:
430.97
Purity:
99.33%
CAS Number:
[1440796-75-7]
Formula:
C21H35ClN2O5
Target:
GlyT|||5-HT Receptor|||P2X Receptor
T9833
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