Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
Molecular Weight:
4200.93
CAS Number:
[230299-95-3]
Formula:
C185H304N68O43S
Target:
Apelin receptor|||HIV Protease
TP2094
* VAT and and shipping costs not included. Errors and price changes excepted
