TRV-120027 TFA

Product Overview

• Article Name: TRV-120027 TFA
• Biozol Catalog Number: TGM-TP2158
• Supplier Catalog Number: TP2158
• Alternative Catalog Number: TGM-TP2158-1MLX10MM(INDMSO),TGM-TP2158-1MG,TGM-TP2158-5MG,TGM-TP2158-10MG,TGM-TP2158-25MG,TGM-TP2158-50MG,TGM-TP2158-100MG,TGM-TP2158-200MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: TRV-120027 TFA (1234510-46-3 free base)

Product Description

TRV-120027 TFA is an angiotensin II-mediated vasoconstriction inhibitor and increases cardiomyocyte contractility. TRV-120027 TFA is a beta-arrestin-1-biased AT1R agonist engaging ß-arrestins while blocking G-protein signaling[1]. TRV-120027 TFA induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling and promotes the formation of a macromolecular complex composed of AT1R-beta-arrestin-1-TRPC3-PLCgamma at the plasma membrane.

Product Properties

• Molecular Weight: 1040.1
• Purity: 97.45%
• Formula: C45H68F3N13O12
• Target: TRP/TRPV Channel|||RAAS|||Arrestin

Images

TP2158