CCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter beta-catenin levels but blocks transcription at the beta-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
Molecular Weight:
347.84
CAS Number:
[305372-78-5]
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