NCX 466 ((aS)-6-Methoxy-a-methyl-2-naphthalene acetic acid (5S)-5,6-bis(nitrooxy)hexyl ester), CAS [[1262956-64-8]]

Product Overview

• Article Name: NCX 466 ((aS)-6-Methoxy-a-methyl-2-naphthalene acetic acid (5S)-5,6-bis(nitrooxy)hexyl ester), CAS [[1262956-64-8]]
• Biozol Catalog Number: USB-145683
• Supplier Catalog Number: 145683
• Alternative Catalog Number: USB-145683-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor (CINOD). Inhibits COX-1 and COX-2 while releasing NO. Demonstrates higher efficacy than naproxen, its congener drug, in reducing levels of profibrotic cytokine transforming growth factor-beta and oxidative stress in a mouse model of bleomycin-induced lung fibrosis. Orally available. Sequence: C20H24N2O9 Solubility: DMSO (~100mM), Ethanol (~100mM) Molecular Weight: ~436.41 Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 436.41
• Purity: ~98% (HPLC)
• Form: Supplied as a pale yellow oil.
• CAS Number: [1262956-64-8]